The SHAPE insurance-claims study found tirzepatide at 16.5% and semaglutide at 14.1% over one year
More than three quarters of the patients had had a previous myocardial infarction, and nearly one quarter had chronic heart failure
Muscle loss with GLP-1RAs is probably proportional to the extent of weight loss, and resistance exercise with adequate protein intake is recommended to preserve muscle mass and function
You can dive deeper into each injectable in our Semaglutide vs
The most common side effects of tirzepatide are gastrointestinal, including nausea (12-24%), diarrhea (12-17%), vomiting (6-10%), constipation (6-11%), and decreased appetite
It works by regulating appetite, increasing satiety, and reducing food intake, thereby supporting sustained weight loss when combined with a reduced-calorie diet and increased physical activity